Keep SEO in mind from the start. So, even when you can't optimize everything from the beginning, build website/blog, etc. in a way it can easily be optimized later – especially if you bring in a new person or freelancer to do it. (So the new person doesn't have to "clean up" first.
Key word research, everything builds on top of that. Low competition, high traffic sweet-spot. If you get that right, everything else is will fall in to place easier.
. . . . and yes - pick a domain that matches your keyword
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