HistoAtlas is a free, open web atlas that maps cancer tissue morphology to molecular programs and patient survival across 21 cancer types. We analyzed 6,745 H&E-stained diagnostic slides from TCGA, extracted 38 quantitative histomic features (tumor morphology, immune infiltration, spatial organization, cell densities), and precomputed 10,000+ statistical associations linking tissue architecture to genes, pathways, mutations, immune subtypes, and clinical outcomes. 100% free. No login.
Hi Product Hunt! I'm Pierre-Antoine, the maker of HistoAtlas.
The problem: Cancer pathology slides contain rich morphological information, but there's no easy way to systematically explore how tissue architecture connects to molecular data and patient outcomes across cancer types. Existing tools like cBioPortal focus on genomics.
What I built: HistoAtlas takes 6,745 diagnostic slides from TCGA, extracts 38 quantitative features (immune cell densities, tumor morphology, spatial organization), and precomputes every statistical association with genes, mutations, pathways, and survival. The result is a fully interactive web atlas you can explore instantly.
Tech stack: Astro + React 19 (static-first), Tailwind v4, Deck.gl for the UMAP, Recharts for charts. The entire API is pre-generated static JSON: no backend, no database, sub-100ms loads. The analysis pipeline is Python (Cox PH, Spearman, K-means, Benjamini-Hochberg FDR correction).
This is a solo project I built because I wanted this tool to exist for my own research. Happy to answer any questions about the data, methods, or tech!
Try it: https://histoatlas.com
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