Garry Tan

Empirical Heart Health - Don't die of a heart attack

Measure, predict, and prevent your risk of heart disease. Start with 85+ biomarkers for $190, then build a personalized action plan using your results and data from your Apple Watch, Fitbit, Samsung, and Pixel.

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Brandon Ballinger

Hey everyone! We’re Brandon, Raquel, Harish, and Wyatt—we’re a team of doctors and engineers here to help you improve your heart health. We previously worked at Kaiser, Google, and Apple, and ran one of the first studies to use deep learning to detect abnormal heart rhythms using the Apple Watch's heart rate sensor.

Heart disease kills more people than all cancers combined—but it’s also the area of health most in your control. 80% of heart attacks can be avoided, and your risk is predictable using statistical models up to 30 years in advance.

Today, we’re launching Empirical’s heart health program across 30+ states, reaching over 200 million people.

Measure
We're offering a $190 test measuring 85+ biomarkers—available at 2,200+ locations nationwide. This includes key biomarkers like:
* ApoB: every 10 mg/dL drop cuts heart disease risk by 9%
* Lp(a): up to 6x more atherogenic than regular LDL
* Cholesterol & Triglycerides: core inputs into heart attack risk predictors.

Predict
Next, we show how your heart attack risk could change by age 70—
* If you do nothing
* If you follow a tailored plan with medication, diet, and exercise

Many people cut their risk by 50% or more with the right changes.

Prevent
Then, we help you build a personalized action plan.

“Eat less red meat.” “Eat more greens.” You’ve heard it all before. This is different. We build a biomarker-driven nutrition plan tailored to your bloodwork—targeting the exact nutrients that matter for your heart. These tailored plans have been shown in the medical literature to be about twice as effective as a simple "eat more fruits and vegetables" diet.

And tracking? Just snap a photo of your meal. We’ll use AI to analyze nutrients like fiber, potassium, sodium, saturated fat, and more.

Help us save one million people from heart disease by 2027--spread the word or get your results now.

Linus Wong

@bballinger Pretty cool that you also test for Lp(a)! I just was reading about that in the last couple of weeks. :)

What are the top predictive markers you test for that wouldn't be typically included in a routine physical for a non-senior citizen?

Brandon Ballinger

@qix0tic aside from Lp(a), Apob, hs-CRP (inflammation), and the various nutrients (iron, potassium, etc) usually aren't part of a routine physical (and are usually denied by insurance).

Yong Woo Shin

Wow your tagline is really straightforward! I don't want to die of a heart attack too 😂

Is your product made especially for patients or elderlys, or for all people(who don't want to die)?

By the way, congratulations @bballinger!

Brandon Ballinger

@pritraveler Empirical is for anyone with a heart. :)

A lot of people do encourage their parents to try it, since as you alluded to, risk of heart disease does go up as we get older.

Kyrylo Silin

Congrats on the launch! It looks polished! Do you think I should run this by my doctor first, or is it safe to use right away?

Brandon Ballinger

@kyrylosilin never hesitate to run things but your doctor, but the blood test panel is designed to be an appropriate preventive screen for anybody. It's done by a phlebotomist at any of 2,000+ lab locations nation-wide. We also have doctors on staff who order the tests, and do follow up video visits to explain the results and prescribe medication if necessary.

Linus Wong

When you say launching in 30+ states, does that mean I can get prescriptions if I'm in one of those states? Are your doctors part of any insurance provider networks? Or if out-of-network, will you do the legwork to check if my plan includes the prescription in its formulary and file for payment on my behalf, or is everything out of pocket first and up to me to file a claim?

Harish Kilaru

@qix0tic Our doctors are licensed in 30+ states and can provide prescriptions if needed based on your bloodwork or symptoms. We're in-network with most major insurance carriers including Anthem / Elevance, Aetna, HealthNet, and United Healthcare. The lab test is cash pay, but your follow-up appointment and medications may be covered depending on your plan.

Marcelo Kunze

Nice! Has Bryan Johnson seen this?

Brandon Ballinger

@marcelokunze not yet! But I think he'd be interested. Do you know him? :D

Marcelo Kunze

@bballinger Yeah let me text my buddy Bryan! No, just kidding I don't sadly... But congrats with the launch man, looking nice!

Elaine Tsai
Cool launch! 85+ biomarkers sound like a lot. Are there some that are more important than others? And how often should I be retesting?
Brandon Ballinger

@etsaii If there were only two biomarkers for heart health, then ApoB and Lp(a) are the two most important. ApoB is basically a more accurate measure of heart attack risk than LDL cholesterol. And Lp(a) is a genetically-determined risk.

If I can do a third, I'd do inflammation. :)

Garrett Wu

Does the initial test measure biomarkers that change over time? Is it helpful to go back for testing periodically?

Brandon Ballinger

@garrett_wu most biomarkers do change in response to diet, medication, and exercise.

For example, ApoB is the best measure of heart disease risk -- it'll change if you reduce saturated fat, increase fiber, and (of course) try a cholesterol-lowering medication.

hs-CRP is inflammation -- it'll change if you change alcohol consumption and remove refined carbs.

The one exception is Lp(a), which is roughly your genetic risk of heart disease. That's stable through your lifetime (although there are drugs currently being trialed to lower it!).

Divyansh Tiwari

Really love the mission behind this! Making heart health more accessible and personalized with data-driven insights is such a meaningful step. Excited to see the impact this creates.

Brandon Ballinger

@divyansh_tiwari7 thanks Divyansh! Our goal is save one million people from heart disease. Let me know if you have feedback as you try the product!

Kay Kwak

The Empirical heart health initiative is a remarkable convergence of medical insight and engineering excellence. It’s a powerful reminder that data-driven healthcare can truly transform lives.

Brandon Ballinger

@kay_arkain thanks, we think so too! Let me know if you have any feedback on the product.

Erliza. P
Finally a heart health solution that doesn't just measure, but helps you actually improve! The wearable integration means continuous monitoring, not just one-time tests. That personalized action plan could be life-changing for many.
Justin Ko
Absolutely love this! Visibility into your health and understanding your biomarkers are the first step for good preventative healthcare
Brandon Ballinger

@justin_ko thank you! We think so too. :)

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